Next summer's Epigenetics GRC (I'm co-chairing with Deborah Bouch'is) is shaping up nicely with an all-star lineup of speakers working on a broad range of organisms and systems and everything from molecular mechanisms to new phenomena. Apply and put it on your calendar! www.grc.org/epigenetics-...

Our study published today @science.org shows that X-chromosome inactivation (XCI) attracts L1 mutations to the human X chromosome: doi.org/10.1126/scie... With outstanding Perspective from @aurelien-doucet.bsky.social & @retrogenomics.bsky.social: doi.org/10.1126/scie...

🚨 Job Alert - Please share 🙏 Interested in 3D gene regulation in development & evolution? 🤓🧬 💥 Our lab at @cabd-upo-csic.bsky.social is expanding! ✅ 4 years fully funded PhD position 💻🧪 Experimental or computational backgrounds welcome 👇 Details below #PhDPosition #PhDOpportunity #AcademicJobs

Doing a Master or PhD and interested in Developmental Biology? Join the free Institut Curie developmental biology course in beautiful Paris this fall! Great speaker lineup, check: training.institut-curie.org/courses/deve... Registration deadline Sept. 18 2026.

Hello World ! We have another postdoc position open in the lab! Are you a freshly minted Ph.D. with a passion for chromatin and evolution ? Come join our ERC project #EvoEpi ! Inclusive environment + cool people + great science = success details 👉 tinyurl.com/3r6zk54n Repost are always appreciated

Hi #TEsky, please remember that we have an amazing community in the TransposonsWorldWide slack channel (join.slack.com/t/transposon...), which I encourage you to join. Another great resource is tehub.org. Please share !

Join TransposonsWorldwide on Slack

Slack is a new way to communicate with your team. It’s faster, better organized, and more secure than email.

join.slack.com

We are looking for someone to lead the new Facility for Protein Biochemistry & Biophysics at the MPI of Immunobiology and Epigenetics in Freiburg — please spread the word and apply if you are interested!

Max Planck Institute of Immunobiology and Epigenetics@mpi-ie.bsky.social · last mo.

🚀 Job alert: We’re starting a new Facility – and you can lead it! The MPI-IE & @mariekeoudelaar.bsky.social are hiring a Head of Protein Biochemistry & Biophysics to launch and lead a brand-new Core Facility in Freiburg 🇩🇪. Once-in-lifetime-chance. Details ⬇️ jobs.ie-freiburg.mpg.de/jobposting/b...

Yesterday, half of #Freiburg’s business world gathered at the Europa-Stadion: 5k company run #b2run. We were there too – driven by curiosity – with runners from the @flurylab.bsky.social @julianeg.bsky.social @jumanaaha.bsky.social labs & other departments of the MPI-IE. Congrats to all finishers! 💪

My first PhD paper is out in Nucleic Acids Research! We describe "Ab-trapping" - an antibody artifact that distorts assays relying on antibody diffusion (microscopy, CUT&Tag, CUT&RUN). The revisions made the story much stronger. Check it out! doi.org/10.1093/nar/...

Antibody-trapping presents a widespread pitfall for microscopy and genomics in the nucleus

Abstract. Chromatin has a complex 3D structure and diverse binding proteins that coordinate the genome’s most essential functions. Many microscopy and geno

doi.org

Applications are open for the international course “Developmental Biology” organized by the Institut Curie in partnership with @sorbonne-universite.fr 📅 Oct. 19–28, 2026 (Paris) ⏳ Jul. 19 & Sept. 18 🔗 training.institut-curie.org/courses/developmental-biology-2026

🚨Preprint Drop🚨 We are very pleased to release our study on DNA methylation dynamics at enhancers during ESC differentiation! This work was led by Marlet Morales-Franco and Priscillia Lhoumaud 🧵(1/13) www.biorxiv.org/content/10.6...

Dual profiling of DNA modifications with enhancer features during the exit of naive pluripotency

Cis-regulatory elements, such as enhancers, play an essential role in coordinating gene expression programs during cellular transitions. As such, substantial efforts have been made to characterize enh...

biorxiv.org

📣 POSTDOC position available in the Feschotte Lab at Cornell to work on #TRANSPOSONS! More details below. Pls send informal application or inquiry ASAP by DM or email to cf458_at_cornell.edu. Pls spread the word 🙏 #TEsky www.thefeschottelabatcornell.com

We are over the moon! 🎈 Dr. Marieke Oudelaar joins the MPI-IE as a new #MaxPlanck Director, heading the newly established Department of Genome Biology She studies how the 3D folding of DNA controls gene expression – more details below ⬇️ Welcome to #Freiburg, @mariekeoudelaar.bsky.social!

Marieke Oudelaar becomes new Director at MPI-IE in Freiburg

ie-freiburg.mpg.de

🚨Happy to share a new PreLight covering the latest #preprint by the Meissner lab (@molgen.mpg.de) on acute SUZ12 degradation during TLS formation. A work brilliantly executed by @dannimklee.bsky.social et al. Get to know more about him and his work here ⤵️ prelights.biologists.com/highlights/t...

Temporal degradation of PRC2 uncovers specific developmental dependencies - preLights

Pairing acute SUZ12 degradation + simplified embryoids, Ming-Kang Lee et al. pinpoint time-dependent sensitivities to PRC2 loss. A meticulous experimental approach applicable to the functional stage-s...

prelights.biologists.com

New paper out in @cp-cellstemcell.bsky.social. We uncover unexpected complexity in how metabolism changes when the embryo implants or when stem cells exit naive pluripotency, revealing a central role for dynamic TCA cycle rewiring in cell fate decisions. www.cell.com/cell-stem-ce...

TCA cycle rewiring underpins histone acetylation sourcing and cell-fate transitions during exit from naive pluripotency

Using carbon tracing and functional experiments, Kafkia, Pladevall-Morera, et al. show that TCA cycle rewiring underlies mouse embryo implantation and the exit from naive pluripotency. In this context...

cell.com

New Preprint alert!🚨 Super excited to share my postdoc work now on BioRxiv. How does PRC2 loss lead to developmental failures? We combined rapid protein degradation with TLS embryoid models to uncover temporal and lineage-specific dependencies 🧬. Preprint: doi.org/10.64898/2026.04.18.719361

plz repost 🙏 we are looking for a technician to start this summer/fall for 1-2 years to work with me at Cornell in the labs of @cedricfeschotte.bsky.social and Andy Clark, in collaboration with @corriemoreau.bsky.social on flies & termites 🪰🐜🧬🔬 Ithaca is gorges! jobs.hr.cornell.edu/us/en/job/WD...

CALS- Technician I- Molecular Biology and Genetics in Ithaca, New York, United States of America | Research & Instructional Support at Cornell University

Apply for CALS- Technician I- Molecular Biology and Genetics job with Cornell University in Ithaca, New York, United States of America. Research & Instructional Support at Cornell University

jobs.hr.cornell.edu

A new study shows how different regulatory genetic elements control when a key developmental gene is active in the body. The findings could explain subtle differences seen in patients with congenital limb malformations, for which the underlying disease mechanisms often remain unknown.

Waves of regulation control an important developmental gene

In a new study published in Genes & Development, research led by Dr Lila Allou at the MRC Laboratory of Medical Sciences (LMS) in London and Professor Stefan Mundlos at the Max Planck Institute for Mo...

lms.mrc.ac.uk

In this interview, @juliabatki.bsky.social, FMI’s newest group leader, reflects on the early curiosity that drew her to science, why FMI is the right home for her lab, how studying cell clearance could help us understand disease, and her love of improv. www.fmi.ch/news-events/...

Curiosity, cell clearance, and improv: A chat with Julia Batki

In this interview, Julia Batki, FMI’s newest group leader, reflects on the early curiosity that drew her to science, why FMI is the right home for her lab, how studying cell clearance could help us un...

fmi.ch

🚨 Why can’t mammals regenerate limbs like frog tadpoles or salamanders? In our new paper in @science.org , we show that species-specific oxygen sensing acts as a gatekeeper for initiating limb regeneration 🐭🐸 🔗 www.science.org/doi/10.1126/... #EvoDevo

The research highlight of our recent work on nuclear speckles is online. The photo choice is eggcellent. Happy Easter! 🌸🐰🥚 www.nature.com/articles/s41...

Nuclear speckles of GC richness - Nature Reviews Molecular Cell Biology

Nuclear speckles support the splicing of levelled exon–intron architecture transcripts, and their evolution shaped genome organization in amniotes.

nature.com

Yolanda and I enjoyed writing this review on X-chromosome reprogramming in the mammalian germline. 👇 Hope you'll enjoy reading it too! @biochemsoc.bsky.social #epigenetic #germline #XCI @igmm-montpel.bsky.social @biolum-montpellier.bsky.social @umontpellier.bsky.social

Yolanda Moyano Rodríguez@yolandamr.bsky.social · 4mo ago

Happy to share our new review on X-chromosome reactivation in the germline, just published in @biochemsoc.bsky.social Transactions! We highlight the latest discoveries on how this epigenetic mechanism unfolds during mammalian germline reprogramming. Hope you enjoy the read 😊

It is a beautiful day in the TriRhena region. ☀️ 😎 Perfect for traveling to today’s Gene Regulation at @igbmc.bsky.social in Strasbourg 🇫🇷. Check out the program with exciting talks in chromatin, transcription & ZGA including the NewPI talk by @simonelsasser.bsky.social.

TriRhena Gene Regulation Club

The TriRhena Gene Regulation Club is a one-day symposium that brings together researchers from France (IGBMC), Germany (MPI-IE) and Switzerland (FMI) who share a common interest in gene regulation.

ie-freiburg.mpg.de

Very excited to announce the FIRST symposium on epigenome editing! These tools are becoming widely used in mol bio, ag & therapy. It's time to bring leaders together to discuss this rapidly growing and exciting field. And why not in Paris! Please register & share! (1/2) ctrlepiedit.sciencesconf.org

I am very happy to share that I've started my new position @upcite.bsky.social and opened my lab @institutimagine.bsky.social 🎉 In the lab we will study how differences in X-linked gene dosage between the sexes affect fetal growth and survival and contribute to sex differences later in life 👩‍🔬🧪🧬🧫

Find our latest Perspective article in Nature Genetics on "The role of KRAB zinc-finger proteins in expanding the domestication potential of transposable elements" at www.nature.com/articles/s41..., with implications for the future of research on the cause of human disease.

The role of KRAB zinc-finger proteins in expanding the domestication potential of transposable elements - Nature Genetics

This Perspective explores the co-evolution of transposable elements and KRAB zinc-finger proteins in relation to their integration into human gene regulatory networks, highlighting their potential eff...

nature.com

We wrote a piece on how easy it is to write gene regulatory sequences. - Turns out, it isn't that easy even though we know a lot about cis-regulation. huge credit to @carldeboer.bsky.social to seeing this through so our thoughts aren't lost. I promise, it's a worthwhile read!

Carl de Boer@carldeboer.bsky.social · 5mo ago

We wrote a perspective "How to build the regulatory genome: a constructionist guide to the cis-regulatory code", out in Development yesterday. Title says it all. Find it here: journals.biologists.com/dev/article/...

Our most recent work on the “function and evolution” of #nuclear-speckles is now online at Cell @cp-cell.bsky.social doi.org/10.1016/j.ce... Read the thread👇 for the highlights of our findings.

🤩💪 Out now! 3D regulatory hubs in sex determination With @mamartirenom.bsky.social & Capel labs, led by @imotagom.bsky.social & @jrotwitguez.bsky.social 1️⃣ METALoci – explore #3DGenome 🧬 2️⃣ Non-coding region controlling Fgf9 🧩 3️⃣ Meis genes = new key players 🌟 👉 rdcu.be/e5sm2 1/n Bluetorial 👇

Chromatin spatial analysis by METALoci unveils sex-determining 3D regulatory hubs

Nature Structural & Molecular Biology - METALoci, a new three-dimensional genome computational tool, reveals a major rewiring of regulatory interactions during sex determination. By combining...

rdcu.be

We're recruiting a PhD student to try and understand stress memory and gene function, using gene editing, in trees! #plantscience

KleineVehnLab@kleinevehnlab.bsky.social · 6mo ago

PhD opening Join a collaborative, interdisciplinary project the Excellence Cluster Future Forests @uni-freiburg.de, working on CRISPR/Cas in poplar to understand how trees cope with climate stress. Apply here: uni-freiburg.de/en/job/00004... @dompsfr.bsky.social @biologyunifreiburg.bsky.social