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Marco Enriquez

@marcoenriquez18.bsky.social

10 Posts109 Follower111 Folgt
Cell - a Cell Press journal@cp-cell.bsky.social · 7d ago

Now online! Basement membrane turnover controls cell shape

Basement membrane turnover controls cell shape

Basement membranes are scaffolds of proteins, like collagen, that give organs shape. During development, basement membranes must adapt to the growing organ. We infer how fast the basement membrane adapts by measuring collagen turnover. We find that perlecan, another basement membrane protein, regulates collagen turnover to control organ shape.

dlvr.it

Joshua Tran@joshuatran.bsky.social · last wk.

💡New Preprint! How does a cell control which way a membrane bends? ESCRT-III has the remarkable ability to reshape membranes and drive reverse-topology fission, yet a fundamental question has remained: what determines the direction of membrane remodeling? www.biorxiv.org/content/10.6...

Direction of ESCRT-III-dependent membrane bending emerges from bilayer asymmetry

In cells, ESCRT-III is unique in mediating fission of membrane necks from inside, a process called reverse-topology fission. Yet, in vitro, the complex primarily assembles outside membrane necks and m...

biorxiv.org

Vanni Lab at UNIFR, Switzerland@labvanni.bsky.social · last yr.

Happy to share the latest work from the lab, led by @mudgal17.bsky.social‬, in collaboration with the Weis lab @ethzurich.bsky.social. How do nuclear membranes fuse during NPC assembly? We answer this question in our latest work, where we identify a new mechanism for membrane fusion… (1/13)

bioRxiv Cell Biology@biorxiv-cellbio.bsky.social · last yr.

A conserved mechanism of membrane fusion in nuclear pore complex assembly https://www.biorxiv.org/content/10.1101/2025.07.21.665908v1

Nature Cell Biology@natcellbio.nature.com · last mo.

☕Mani, Tardif, Rossier et al. show that mechanical stress triggers caveolin-1 release from caveolae, enabling its diffusion in the plasma membrane and interaction with signaling effectors to regulate intracellular signaling. 👉https://rdcu.be/frvPe www.nature.com/articles/s41...

Diffusing caveolin-1 scaffolds regulate mechanosignalling - Nature Cell Biology

Mani, Tardif, Rossier et al. show that mechanical stress triggers caveolin-1 release from caveolae, enabling its diffusion in the plasma membrane and interaction with signalling effectors to regulate ...

nature.com

Phil Abitua@ohnolog.bsky.social · last mo.

Annual killifish continue to surprise us: they make neutrophils before almost every other cell type, even before gastrulation. Neutrophils usually arise from the lateral plate mesoderm (forming in cyan), but in killifish they are already patrolling around the embryo in gold. tinyurl.com/killiphil

Chise@sailorrooscout.bsky.social · last mo.

GOOD NEWS! A personalized mRNA vaccine, known as mRNA-4157, has shown promise in keeping melanoma, a deadly skin cancer, from returning. FIVE years later, NEARLY 70% of people in the vaccine group are CANCER-FREE. The vaccine also cut a person’s risk of the cancer metastasizing by NEARLY 60%.

A personalized vaccine for melanoma cut the risk of cancer returning after five years

If the vaccine is effective in a late-stage trial, it would be “paradigm-shifting,” one expert said.

nbcnews.com

Elias Spiliotis@septinlab.bsky.social · 2mo ago

Our newest review on septins as makers & breakers of membrane contacts in J Neurochem Fun writing with new PhD grad (and FASEB Septin Conference A/V Assistant Extrordinaire) TJ Holt Thanks @mcmurraylab.bsky.social @sergemostowylab.bsky.social for input. onlinelibrary.wiley.com/doi/10.1111/...

Septins in the Middle—Makers and Breakers of Membrane Contact Sites

Septins are a family of GTP-binding proteins that assemble into heteromeric oligomers and polymers, associating with specific membrane domains and organelles according to their subunit composition. G...

onlinelibrary.wiley.com