🧵New paper from the lab @isd-research.bsky.social @lmu-klinikum.bsky.social @lmu.de published in @natneuro.nature.com: We developed a highly reproducible 3D human brain tissue model (3BTM) that enables studying microglial phenotypes in health and disease! #OA PDF here: rdcu.be/fxLou Thread👇: 1/11

Well done - especially to our BMC group leader Martin Kerschensteiner

LMU München@lmu.de · last mo.

🙌 Congratulations! Three #ERC Advanced Grants for #LMU researchers: Philosopher @alyssaney.bsky.social, neuroimmunologist Martin Kerschensteiner, and chemist Thomas Carell have each been awarded an Advanced Grant by the @erc.europa.eu. #ERCAdG #LMUMunich www.lmu.de/en/newsroom/...

Big congrats Veronica, and all the best for your lab!

M. Veronica Pravata@mveronicapravata.bsky.social · 2mo ago

I am thrilled to announce I’ve been awarded a DFG Emmy Noether grant to establish the Pravata Lab at FAU! 🎉🔬 We'll explore how glycosylation shapes human brain development & evolution using neural organoids. And... we are hiring! 🧵👇 @dfg.de @fau.de

🏆 Top-ranked: LMU Munich is the best German #university in this year’s Center for World University Ranking (CWUR). Within the EU, #LMU ranks 8th and globally 51st among the 21,291 universities assessed. Congratulations! 🙌 🎉 #LMUMunich #CWUR #Ranking

🏥 Startschuss am Campus Großhadern/Martinsried der LMU München: Heute wird das neues neue #Zentrum für Diagnostik und translationale Forschung des Max von Pettenkofer-Instituts für Hygiene und Medizinische Mikrobiologie (DIAG) eröffnet. 🔬 www.lmu.de/de/newsroom/... #LMU #DIAG

The absolute dream paper for any #cerebrovascular developmental biologist !! Congrats to @nicolasrenier.bsky.social, @alexdubrac.bsky.social and their teams !

The spatiotemporal dynamics of postnatal vascularization in the mouse brain

Whole-brain tissue clearing and spatial transcriptomics were applied to map postnatal vascular development in the mouse brain, identifying three coordinated phases that link vascular growth to neurona...

cell.com

Very proud of our new paper, which I worked on in the @paquetlab.bsky.social for the past years! 👩‍🔬 Out this week in Science Translational Medicine @science.org. Find all the exciting details on what we found here 👇

PaquetLab@paquetlab.bsky.social · 4mo ago

🧵New paper from the lab @isd-research.bsky.social @lmu-klinikum.bsky.social @lmu.de in STM @science.org! A human #iPSC-derived #Tauopathy model that endogenously develops late-stage Tau pathology. Free personal PDF: www.science.org/eprint/5H5YD.... Here's what we found👇 1/10

🧵New paper from the lab @isd-research.bsky.social @lmu-klinikum.bsky.social @lmu.de in STM @science.org! A human #iPSC-derived #Tauopathy model that endogenously develops late-stage Tau pathology. Free personal PDF: www.science.org/eprint/5H5YD.... Here's what we found👇 1/10

Big congrats to our PhD student @ishitaajith.bsky.social !!

Ishita Ajith@ishitaajith.bsky.social · 4mo ago

Thrilled to cap my time at Oxford with a first first-author paper in @alzdemjournals.bsky.social ! 🧠✨ Unveiling Aβ-independent effects of Module 42 (AD protein network) on immune function: 5 proteins boost phagocytosis, 7 modulate Ca²⁺ signaling (MDK & TMEFF2 nail both) PDF: doi.org/10.1002/alz....

Munich takes the top two spots in the FT ranking of Europe’s startup hubs — UnternehmerTUM #1, Start2 Group #2. Strong science, engineering depth, & real bridges between research + entrepreneurship. Huge opportunity ahead in part. for AI + bio/med. 🚀 www.ft.com/content/ab05...

FT ranking: Europe’s leading start-up hubs 2026

View the top centres providing business incubator and accelerator programmes

ft.com

Losing sleep over #iPSC transgene silencing after differentiation? Same here. Bright in iPSCs. Gone after differentiation. Our paper in @cp-cellstemcell.bsky.social maps what actually keeps expression on👇 www.cell.com/cell-stem-ce... 🔗 Free access (50 days): www.sciencedirect.com/science/auth...

Many thanks @nature.com for selecting our image of a fully #iPSC derived #BBB (#blood-brain-barrier) as 'Image of the Week' in Nature Briefings: mailchi.mp/nature/trans... 😀 Find the image in action in our primary research paper here: rdcu.be/eUIl3

Image of the Week: Congrats to the team of González-Gallego J et al., Nat Neurosci. 2026 for this lovely award in Nature Briefing 🏆 🖼️ @judit-gonzalez.bsky.social @paquetlab.bsky.social (->Fig 2b www.nature.com/articles/s41...)

PaquetLab@paquetlab.bsky.social · 8mo ago

New paper out today at @natneuro.nature.com in collab. with DichgansLab @isd-research.bsky.social @lmumuenchen.bsky.social: We developed a fully #iPSC-derived human model of the #BBB #blood-brain-barrier and applied it to study neurovascular disease (NVD)! #OA PDF here: rdcu.be/eUIl3 Thread👇 1/10

🏛️ 200 Years of LMU in Munich 🎓 Founded in 1472, relocated from Landshut to Munich in 1826 — today LMU celebrates 200 years in Munich and inaugurates Prof. Dr. Matthias H. Tschöp as President.

Our paper is (finally) out in Cell today! CRISPR screens in iPSC-derived neurons reveal principles of tau proteostasis www.cell.com/cell/fulltex... Great collaborative effort - read more from first author @asamelson.bsky.social below:

CRISPR screens in iPSC-derived neurons reveal principles of tau proteostasis

CRISPR screens in iPSC-derived neurons reveal that the E3 ubiquitin ligase CRL5SOCS4 ubiquitinates tau, that CUL5 expression is correlated with resilience in human Alzheimer’s disease, and that electr...

cell.com

asamelson@asamelson.bsky.social · 6mo ago

After a long review process, I'm excited that our paper is finally in print: www.cell.com/cell/fulltex... TL;DR: We use CRISPR screens in iPSC-derived neurons to find a new tau E3 ligase and a relationship between oxidative stress, the proteasome, and tau proteolytic fragments. More below 👇

#ECR save the dates! 🗓️ In der Reihe #PROSPECTS informiert unser Team #Karriereförderung auch 2026 regelmäßig über die Fördermöglichkeiten bei der DFG. Hier haben wir die Infotalks für die erste Jahreshälfte. Teilnahme ohne vorherige Registrierung möglich, Link erscheint hier. 👉 sohub.io/bvv0

The reckless human embryo genome editor, He Jiankui, known as China's Dr. Frankenstein, is back at it. "People were not yet ready to accept what I was doing." We're still not. nytimes.com/2026/01/13/w...

China’s ‘Dr. Frankenstein’ Thinks Time Is on His Side

nytimes.com

Stem Cell Reports is calling for applications to serve on its editorial team as an Early Career Editor, a prestigious opportunity for outstanding, early-career scientists to help shape the future of stem cell publishing. The deadline to apply is 13 March 2026. https://ow.ly/8iiP50XWscj

🧠 Fully human #iPSC - derived 3D #BBB model with perfusable vessels and key BBB functions. #FOXF2 deletion causes BBB dysfunction, rescued by lipid-nanoparticle delivery of Foxf2 mRNA. 🔗Read a summary of the study on our website: www.synergy-munich.de/news-events/...

Many thanks #Alzforum for featuring our recent studies on iPSC models of the #blood-brain-barrier! And we are also grateful for all the thoughtful comments from experts in the field! www.alzforum.org/news/researc.... Primary papers can be found here rdcu.be/eUIl3 and here rdcu.be/eUImz 🙂

And another new paper with co-first and -last author contributions from the lab at @natneuro.nature.com! Another great collab with DichgansLab @isd-research.bsky.social @lmumuenchen.bsky.social: Foxf2 maintains brain endothelial cell function via Tie2 signaling! #OA PDF: rdcu.be/eUImz Thread👇 1/7

New paper out today at @natneuro.nature.com in collab. with DichgansLab @isd-research.bsky.social @lmumuenchen.bsky.social: We developed a fully #iPSC-derived human model of the #BBB #blood-brain-barrier and applied it to study neurovascular disease (NVD)! #OA PDF here: rdcu.be/eUIl3 Thread👇 1/10

Human – mouse chimeric cultures to study microglia and amyloid pathology; This is a very exciting approach with lots of potential. Congratulations to Vasiliki Panagiotakopoulou! Cell Reports www.cell.com/cell-reports...

Chimeric human organoid and mouse brain slice co-cultures to study microglial function

Panagiotakopoulou et al. developed a co-culture system combining human cerebral organoids and mouse brain slices. The model supports long-term study of human microglia, enhances cortical marker expres...

cell.com

Zebrafish indeed rock for imaging! Thanks for digging out this work from my Postdoc again 😀

Zebrafish Rock!@zebrafishrock.bsky.social · 8mo ago

Time-lapse movie of mitochondria (blue) transport within neurons (green) in the tail of a transgenic #zebrafish larva. Credit to @paquetlab.bsky.social. #ZebrafishZunday 🧪

Exciting opportunity to learn about #humanbrainmodels and #singlecelltechnology! July 13-17 2026 we for the first time will offer the Utrecht Summer School titled "Advanced human brain models in the single-cell era" for master and PhD students. Apply now: utrechtsummerschool.nl/courses/life...

🧠Very excited to share our new preprint on microglia in chimeric brain slice cultures 🔬 the chimeric slices offer an opportunity to investigate human microglia in a flexible and physiologically-relevant 3D environment 👉🏼read the full preprint here www.researchsquare.com/article/rs-8...

🎉 So excited to receive the #DeutscherStudienpreis (German Thesis Award) by the @koerber-ip.bsky.social handed over by the German Head of Parliament @bundestag.de. I got recognized for my work on novel human experimental models of dementia in the lab of @paquetlab.bsky.social.

She did it! Huge congrats to @angelikadannert.bsky.social from our lab, who received the @koerber-ip.bsky.social DSP award for the best biomedical research thesis in Germany, directly from Julia Klöckner, head of the German parliament @bundestag.de!!! 🍾

Big congrats to Mila @milaborri.bsky.social from the lab for obtaining a EU-funded #MCSA postdoc fellowship!! We look forward to working with you on developing #iPSC based vascularized human brain tissue models to study major #brain diseases, such as #Alzheimer's and #stroke!

Mila Borri@milaborri.bsky.social · 10mo ago

I'm proud to share that this week I started my position as #MSCA Postdoctoral Fellow in the @paquetlab.bsky.social at #LMUMunich! For the coming 2 years, I'll optimize a human in vitro vascularized 3D brain tissue model and apply it for the study of #neurodegeneration. 👩‍🔬 🔬 🧠 #hiPSCs #3DTissueModel

Great conference! Very happy to join again.

Stefan Hauser@stefanhauser.bsky.social · 10mo ago

Join us for 𝗦𝘁𝗲𝗺 𝗖𝗲𝗹𝗹𝘀 𝗶𝗻 𝗡𝗲𝘂𝗿𝗼𝘀𝗰𝗶𝗲𝗻𝗰𝗲, 𝟮𝟱𝘁𝗵-𝟮𝟳𝘁𝗵 𝗼𝗳 𝗙𝗲𝗯𝗿𝘂𝗮𝗿𝘆, 𝟮𝟬𝟮𝟲 in Tübingen, Germany. Register here until 30th of November: 👉 stemcelltuebingen.com Speaker slots and stipends available Please repost and spread the news! @dzne.science @hih-tuebingen.bsky.social @tueneurocampus.bsky.social