Fat storage in the body relies on specialized structures called lipid droplets. In a new Science study, researchers identified the microprotein adipogenin as a regulator of adipocyte lipid droplet size, revealing a key mechanism in lipid homeostasis. Learn more this week: https://scim.ag/4nFEGO7

A pleasure to write this short review on lipid droplets for @jcb.org together with Will Prinz and amazing artist Emma Reynolds! We discuss 5 pervasive questions surrounding these remarkable little lipid organelles. doi.org/10.1083/jcb....

New review: Henne (@hennelab.bsky.social), Reynolds, and Prinz discuss recent discoveries and enduring mysteries in the lipid droplet field. rupress.org/jcb/article/... #Biochemistry #CellMetabolism #LipidDroplets

Our protocol for gene editing is online and all plasmids are on @addgene.bsky.social! CRISPR away everybody and get in touch if you need anything 🤩

STAR Protocols@cp-starprotocols.bsky.social · last yr.

Protocol for fast antibiotic resistance-based gene editing of mammalian cells with CRISPR-Cas9 #protocol #starprotocols #cellpress

Nodal modulator (NOMO) is a force-bearing transmembrane protein required for muscle differentiation, say Brigitte Naughton, Christian Schlieker @schliekerlab.bsky.social and colleagues @yaleschoolofmed.bsky.social: rupress.org/jcb/article/... #StructuralBiology #Biochemistry #Organelles #Membrane

Naughton et al. @schliekerlab.bsky.social conducted force measurements within the endoplasmic reticulum (ER) measuring forces in the piconewton range uncovering a critical role for NOMO as force-bearing transmembrane protein that is critical for myogenesis. rupress.org/jcb/article/...

Nodal modulator (NOMO) is a force-bearing transmembrane protein required for muscle differentiation url: rupress.org/jcb/article/...

We had a great kick-off of our Lipid Metabolism & Neurodegenerative Disease Mini-symposium! Many thanks to all speakers and attendees! #UTSW_science

🧵5 Top Free Alternatives to BioRender for Scientific Illustrations! These five websites offer free scientific illustrations for biologists. Great for presentations, research papers and other research communication needs. Save and share the post!

I am excited to announce that my postdoc work in @hennelab.bsky.social is now online at Cell Reports! Congrats and thanks to all who helped us on this journey!

Henne lab@hennelab.bsky.social · 2y ago

Important to celebrate trainee victories: excited to have Holly Merta's @hollymerta.bsky.social paper out! We use TurboID sub-organelle proteomics to map the ER network. We find calmin/CLMN, an ER-to-actin tether regulating focal adhesions & cell motility. www.sciencedirect.com/science/arti...

Important to celebrate trainee victories: excited to have Holly Merta's @hollymerta.bsky.social paper out! We use TurboID sub-organelle proteomics to map the ER network. We find calmin/CLMN, an ER-to-actin tether regulating focal adhesions & cell motility. www.sciencedirect.com/science/arti...

Spatial proteomics of ER tubules reveals CLMN, an ER-actin tether at focal adhesions that promotes cell migration

The endoplasmic reticulum (ER) is structurally and functionally diverse, yet how its functions are organized within morphological subdomains is incomp…

sciencedirect.com

Following a helpful and pleasant peer-review process, our direct-view oblique plane microscopy manuscript has now been published in Optica: doi.org/10.1364/OPTI... Special thanks to the copy editor who let us keep our cheeky little acknowledgement of the enjoyableness of drinking a cup of tea.

James Manton@jamesdmanton.bsky.social · 2y ago

We present: Direct-view oblique plane microscopy www.biorxiv.org/content/10.1...

Some good news (and fresh science) to break things up! Our work identifying a subpopulation of compositionally unique mitochondria that localize to filopodia and promote cell migration is now @currentbiology.bsky.social! Led by fantastic @madeleinempavey.bsky.social! www.cell.com/current-biol...

Compositionally unique mitochondria in filopodia support cellular migration

Marlar-Pavey et al. determine that a subpopulation of compositionally unique mitochondria, METEORs, dynamically localize to filopodia. Loss of mitochondrial targeting to filopodia correlates with a re...

cell.com

The Zwick lab has landed in the Regenerative Medicine Institute @NYU! I’m incredibly excited to build a team to study how epithelial organs are patterned and remodeled throughout life, with a major focus on the remarkable changes that occur in the maternal body during pregnancy..1/5

Want to follow developments in the field of inter-organelle communication? Follow Contact @contactctc.bsky.social and its latest publications!

Contact: The Journal of Inter-Organelle Communication@contactctc.bsky.social · 2y ago

Contact is here at last #firstpost. 2025 also sees us adding a strapline to our title. Instead of one pithy word, we have 5 more: Contact: The Journal of Inter-Organelle Communication We look forward to sharing new of progress in this scientific field in general and for the journal specifically.

A big congrats to Alia on a successful thesis defense! @themitotracker.bsky.social gave an excellent talk and did the lab proud! 🥳🎉🍾

Applications are still open for the 2025 Leading Edge cohort! Deadline is Feb 3, 2025.

Leading Edge Fellows Program@leadingedgeprogram.bsky.social · 2y ago

Leading Edge is celebrating a milestone: 100 (actually 102!) new assistant professors!!! 🎉🥳🎊 Learn more about them: www.leadingedgesymposium.org/fellows/ Applications are now open for the 2025 Leading Edge cohort! (Deadline Feb 3). You do NOT need to be ready for the job market to apply.

Our collaboration with the Germain Lab is now out in its final form!

Leading Edge is celebrating a milestone: 100 (actually 102!) new assistant professors!!! 🎉🥳🎊 Learn more about them: www.leadingedgesymposium.org/fellows/ Applications are now open for the 2025 Leading Edge cohort! (Deadline Feb 3). You do NOT need to be ready for the job market to apply.

Happy to announce I am serving as Director of the Lipid Metabolism & Neurodegenerative Diseases (LMND) Program at UTSW. Our goal is to stimulate collaborations bridging lipid metabolism & neurological disease. So proud of our lab & their cell biology adventures! #onward_science

If you are at #cellbio2024, please consider coming to the Membrane Contact Sites session tomorrow (12/16) at 5pm in room 29C! Many great talks planned! I will be presenting “Keep Calmin and Carry On: Tethering the ER to F-actin Enables Cell Migration” at 6. Hope to see you there!

Never found my school's 🦋, so I hope it's ok that I'm posting this myself. I'm presenting my poster today on characterizing internal mediators of mitochondrial fission at 11:15am at poster #B143! If you missed my #MitoTalks last month, please stop by! #CellBio24 #mitofission #microscopy

Alia Edington@themitotracker.bsky.social · 2y ago

Finally, If you missed last week's MitoChat & are interested in my work, I will be presenting again at #ASCB24 so keep a look out for that as well!

Beautiful day in sunny San Diego for ASCB #CellBio2024!

Cohen lab will be well represented at #CellBio2024! If you love #Organelles, #MembraneContactSites, and/or #Neurons and #Astrocytes, please come say hello!

A huge congratulations to the winner of JCB's Alan Hall award, Alia Edington from the Friedman lab at UTSW And to the winner of our Norton B Gilula award, Justin Krish Williams from the Schekman lab at UC Berkeley! rupress.org/jcb/pages/al...

So proud of Alia Edington @themitotracker.bsky.social for winning the JCB Alan Hall Travel award to attend ASCB! Thank you @jcellbiol.bsky.social for recognizing the hard work of our trainees! Be sure to check out Alia's talk 5pm Mon. in the organelle subgroup or at poster B143 Sun. 11:15!

Tim@timisstuck.bsky.social · 2y ago

A huge congratulations to the winner of JCB's Alan Hall award, Alia Edington from the Friedman lab at UTSW And to the winner of our Norton B Gilula award, Justin Krish Williams from the Schekman lab at UC Berkeley! rupress.org/jcb/pages/al...

Excited to attend ASCB #CellBio2024! The Henne lab will present on a range of topics this year from molecular tethers that promote cell movement, to lipid transporters, to lipid droplets & metabolic rewiring. Please check out our lab's talks and posters:

🚨For the lucky colleagues attending #CellBio2024 in San Diego, check out our session on 'ER structure and function across cell types' Room28C- Dec18th 09:00am! A fantastic lineup covering the latest across the field. See you there! **Please RT** 🥳 t.co/6eq3cyGlVZ

Hullooooo Cell Biology friends. If you're heading to #CellBio2024 in (hopefully!) sunny San Diego this year, then come and check out our session on 'ER structure and function across cell types' Room28C- Dec18th 09:00am! See you there! **Please RT** 🥳

Q: What's wrong with these plots? A: Pooling cell-level measurements across multiple runs conceals experimental reproducibility. Read more in JCB (with @fritzlaylin.bsky.social @katrinavelle.bsky.social & Dyche Mullins): rupress.org/jcb/article/...